Institute of Rheological Functions of Food (IRFF)

Plasmalogen Extraction Method

Our Institute Developed and Patented Plasmalogens Extraction Methods for Use in Clinical Trials and as Supplements.

Patented Technology: US11066432B2

Problem to be Solved

It enables any superior ether phospholipids to the conventional ones and a method for producing the same in an easy manner on a massive scale, in light of effects of treating and improving brain diseases such as Alzheimer's disease, Parkinson disease, depression and schizophrenia, metabolic diseases such as diabetes, various infectious diseases, and immune disorders.

Solution

Ether phospholipids are obtained from bivalve tissues such as clams and corbicula by extraction processing. The ether phospholipids exhibit significantly superior effects of the above as compared to the conventional ether phospholipids derived from chicken tissues.

Overview

IRFF Genome Institute is proud to present our innovative and patented plasmalogen extraction methods, meticulously developed by Dr. Shiro Mawatari and Dr. Takehihko Fujino. These methods enable the efficient and large-scale production of ether phospholipids, which are essential in treating various neurodegenerative and metabolic diseases.

Patented Extraction Process

Our proprietary extraction technique leverages the unique chemical properties of plasmalogens, particularly their vinyl ether bonds, to isolate and purify these vital lipids from bivalve tissues such as clams and corbicula. This method ensures high yield and purity, making the production process both scalable and economically viable.

Applications in Clinical Trials

The extracted plasmalogens are utilized in clinical trials aimed at evaluating their therapeutic efficacy in treating conditions like Alzheimer's disease, Parkinson's disease, depression, schizophrenia, diabetes, and various immune disorders. Our patented methods ensure that the plasmalogens used in these trials are of the highest quality, providing reliable and consistent results.

Supplements for Health and Wellness

In addition to clinical applications, our plasmalogen extraction methods facilitate the production of dietary supplements. These supplements support neuronal health by acting as antioxidants, reducing oxidative stress, and mitigating neuroinflammation. They also play a crucial role in cell fusion and ion transport, essential for maintaining healthy neuronal function.

Research and Development

Extensive research and clinical studies conducted by our team have demonstrated the efficacy of plasmalogen supplementation in improving cognitive function and reducing disease symptoms. Our methods ensure that plasmalogens retain their biological activity, making them effective therapeutic agents with no reported adverse effects.

Future Prospects

With our patented extraction methods, IRFF Genome Institute aims to advance therapeutic strategies for neurodegenerative diseases and explore further applications in metabolic and immune disorders. Our goal is to make these treatments widely accessible, improving patient outcomes globally.